Showing posts with label Neuroscience. Show all posts
Showing posts with label Neuroscience. Show all posts

Tuesday, 12 April 2016

Why prohibitionism fanatics should stop obstructing research into psychoactive substances


Occasionally in life you get to meet one of your heroes. For me one of the great moments was the time I had the opportunity to meet Professor David Nutt, who is a neuropsychopharmacologist from the west country who was thrust into the media spotlight back in 2009 when the then Home Secretary Alan Johnson forced him out of his job as the government's leading "independent"* drugs advisor for daring to point out that certain prohibited substances like MDMA and cannabis are much less harmful and addictive than legal substances like alcohol and tobacco.

I admire David Nutt for the fact that he was prepared to stand up for his scientific research even though it cost him his job. Aside from his obvious integrity I also admire him because he's a leading expert in neuroscience, which is a field of study I'm fascinated by.

I remember Professor David Nutt decrying the massive obstacles put in the way of research into psychoactive substances by the ideological driven prohibitionists and their "war on drugs". 
He said that trying to conduct research into the brain without using psychoactive substances is like trying to conduct research into the cosmos without telescopes, or research into microbiology without a microscope.

Research findings

The astounding results of research that David Nutt and other scientific experts have conducted into substances like LSD, psilocybin mushrooms, DMT, ketamine and MDMA (in spite of all of the prohibitionist barriers to such research) provide a compelling case that Professor Nutt is absolutely right that psychoactive substances are vitally important tools for understanding the human brain.

Here are some of the fascinating findings over the last few years.

  • University College London conducted brain scans on people using LSD. The results were incredible. David Nutt compared the findings to the discovery of the Higgs Boson in scale of importance.
  • Modern meta-analysis of old LSD studies (that were carried out before the great purge of scientific investigation following prohibition of the drug in the 1960s) has found that there are good signs that LSD could be useful in treating alcohol addiction.
  • Scientific research has shown that prohibited psychoactive substances like LSD and ketamine be used to effectively treat depression.
  • Research has shown that the drug Ibogaine (derived from the traditional medicinal plant iboga) is effective in treating opioid addiction. It has the added benefit of lessening the painful withdrawal symptoms too.


The effect of ideological prohibitionism on scientific research

There are several ways that ideological prohibitionism interferes with scientific research into psychoactive substances. In many places research into proscribed drugs is simply banned. In other places like the US and the UK hugely expensive and time consuming bureaucratic barriers have been erected to deter scientific research.

Another way that the prohibitionist mentality obstructs legitimate scientific research is that most scientific funding organisations won't dare touch such research out of fear of the hysterical shrieking of the right-wing press damaging their public reputation. In a culture in which the drugs debate is dominated by those with the most hysterical voices, it's no surprise that the majority of scientific research into proscribed substances is reliant on the limited funds available from the likes of the Beckley Foundation.

Another way in which the political class are obstructing scientific research into the use of psychoactive substances as mental health treatments is the absurdly anti-scientific and unworkable Psychoactive Substances Bill that was voted into existence in January 2016 and will render all substances that produce a psychoactive effect illegal, even if they haven't even been discovered yet!

Now that we have a growing body of evidence that a large number of currently prohibited psychoactive substances have potential mental health benefits for millions of people who suffer conditions like depression, anxiety, addiction and PTSD, it becomes obvious that a political ideology that continues deliberately obstructing research into these substances is deeply immoral.


It's bad enough that the political establishment continue pushing a morality-not-science based mentality that if people ever begin using substances to have fun, those substances have got to be banned as soon as possible (whether there's evidence that they're harmful or not). But the real kicker is that the political establishment are not just denying people's liberty to have fun, they're preventing people with serious mental health conditions from accessing substances that could really help them.

Conclusion

Instead of concluding with my own opinion on the negative effects of the regressive anti-scientific ideology of the political establishment on legitimate scientific research into psychoactive substances, I'll leave the last word to a scientist who has conducted several of these fascinating research projects, despite all of the barriers put in place by the ideologically driven prohibitionism crowd.

"It would be nice if the government based their policy decisions on scientific evidence, and if they gave that primary consideration rather than secondary. Now they try and fit scientific data into their policies." - Robin Carhart-Harris

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* The reason I put the word "independent" in inverted commas is that if the government advisor can be forced out of his job for saying something that contradicts the prevailing ideology of the government, then they're clearly not independent at all.

Tuesday, 8 February 2011

Psychoquackery



From the very beginning, the so called psycho-sciences (psychology, psychoanalysis, psychiatry, psychotherapy) were built on a foundation of deranged nonsense. Sigmund Freud came out with a lot of pseudoscientific gibberish (all little boys are latent motherfuckers and all little girls fantasise about a good fucking from their dad). To use a phrase that is common to the psycho-brigade this looks like a classic case of projection. 

Even today Freud's ideas still have huge influence over the field, his theory that adult problems can be traced to unresolved conflicts from certain phases of childhood and adolescence is still popular, his descendants also heavily influenced the field and the vast majority of people able to name a famous psychoanalyst would probably come up with Sigmund Freud.
One of "Pavlov's children."
In the early 20th century, psyco-sciences progressed from Freud's deranged pseudoscience to barbaric experiments on animals and people. Most people have heard of Pavlov's dogs and the "conditioned reflex" but few are aware that Pavlov carried out the same experiments on children too, including surgically adding taps to their salivary glands and force feeding them.

Others like William Sargent pioneered some horrifying treatments like insulin therapy (regularly inducing comas with huge insulin overdoses), Electroconvulsive therapy (giving huge electric shocks to the patient in order to "burn out" their mental illness) brain surgery like lobotomies and all kinds of experimental drug therapies. It seems that many of the people working in the field in the early 20th century would be described as psychopaths by today’s standards because of their willingness to inflict unproven and traumatic treatments on people, often with little or no scientific justification.

By the 1950s the idea of treating "deviance" was commonplace. People such as young women who had a child out of wedlock or refused to stop seeing a boyfriend that their parents disapproved of would be institutionalised and given treatments like electroshock therapy and in many cases lobotomies. Many victims of this regime can still be found in mental institutions to this day and have suffered whole lifetimes of bogus psychotherapeutic treatments and institutionalisation just for failing some social conformity expectation in their early years.

Thankfully the "profession" has left some of the worst treatments like insulin induced comas and lobotomies in the past, however the concept of medicalisation of "deviance" and "non-conformity" is still fundamental to the profession. As you can see from the video there is an ever growing cloud of so called psychiatric disorders, the most famous being ADHD for which hundreds of thousands of children are treated with a stimulant called Ritalin (which has pharmacological effects similar to a mix of amphetamines and cocaine). Imagine the public outrage if I were to set up a website aimed at selling amphetamines to children in order to help them stay awake and concentrate on their school work, however the psycho-brigade can get away with it by deflecting criticism with their expertise and qualifications and pointing to the evidence base they have built up to support their methodology of drugging children with powerful stimulants.

The experimental data does show that the kids become less disruptive when they take these powerful stimulants but the methodology of medicalising symptoms like hyperactivity, impulsive behaviour and inattentiveness with extremely powerful drugs at such early ages must lead to medical dependence in the same way that mass institutionalisations of the mid 20th century led to a huge number of completely institutionalised patients.

The creation of medical dependence is clearly beneficial to the big pharmaceutical companies that produce the drugs like Ritalin and to the professional prescribers, who with the right techniques can create lifelong patients out of children with "disorders" like not being able to "sit still and concentrate on boring stuff" which until recent times was considered fairly normal childhood behaviour and treated with corporal punishment in schools. The profession is not only punishing and stigmatising people that display non conformist behaviour they are making a profitable industry out of their medicalised treatments.

The rise of Cognitive Behavioural Therapy has given traditional psychotherapists a lot to worry about. In layman's terms CBT is a methodology that focuses on helping patients to develop the mental skills to overcome their own behavioural problems and has been shown to work in the treatment of anxiety, depression, phobias, insomnia and a range of other "mental disorders". One of the main benefits of CBT is that it can reduce patient reliance on expensive long term drug therapy.

It is no surprise at all that leading establishment psychiatrists such as Andrew Samuels like to use their influence to characterise CBT as "a coup, a power play by a community that has suddenly found itself on the brink of corralling an enormous amount of money". It is frankly disgraceful to see a spokesman for, and proponent of, the traditional and expensive methodology of medicalisation and institutionalisation trying to smear the cheaper and more humanist approach as a bunch of money grabbing usurpers.

I don't see CBT as a magic bullet, but it is much closer to the holistic and humanist approach to mental illness that I favour. To me it is obvious that helping people to work out how to overcome their own problems where possible is a vastly superior approach to trawling their childhood for traumatic experiences and helping them to pin the blame for their situation on things that simply can't be undone, prescribing lifelong regimes of expensive and powerful drugs like stimulants and sedatives and herding patients into institutional care. It is time for the so called experts to get rid of the view of mental health conditions as deviances that can be categorised and medicated and start to see and treat their patients as people.

More info - CCHR